Selected Publications

Seale, P., Sabourin, L.A., Girgis-Gabardo, A., Mansouri, A., Gruss, P., and Rudnicki, M.A. (2000). Pax7 is required for the specification of myogenic satellite cells. Cell 102:777-786. 

Kuang, S., Kuroda, K., Le Grand, F., and Rudnicki, M.A. (2007). Asymmetric self-renewal and commitment of satellite stem cells in muscle. Cell 129:999-1010. 

Le Grand, F., Jones, A.E., Seale, V., Scime, A., and Rudnicki, M.A. (2009). Wnt7a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells. Cell Stem Cell 4:535-547. 

Yin, H., Pasut, A., Soleimani, V.D., Bentzinger, C.F., Antoun, G., Thorn, S., Seale, P., Fernando, P., van Ijcken, W., Grosveld, F., Dekemp, R.A., Boushel, R., Harper, M.E., and Rudnicki, M.A. (2013). MicroRNA-133 controls brown adipose determination in skeletal muscle satellite cells by targeting Prdm16. Cell Metabolism17:210-224.

Price, F.D., von Maltzahn, J., Bentzinger, C.F., Dumont, N.A., Yin, H., Chang, N.C., Wilson, D.H, Frenette, J., and Rudnicki, M.A. (2014). Inhibition of JAK/STAT signaling stimulates adult satellite cell function. Nature Medicine doi: 10.1038/nm.3655. [Epub ahead of print].

McKinnell, I.W., Ishibashi, J., Le Grand, F., Punch, V.G., Addicks, G.C., Greenblatt, J.F., Dilworth, F.J., and Rudnicki, M.A. (2008). Pax7 activates myogenic genes by recruitment of a histone methyltransferase complex. Nature Cell Biology 10:77-84.

Soleimani, V.D., Yin, H., Jahani-Asl, A., Ming, H., Kockx, C.E., van Ijcken, W.F., Grosveld, F., and Rudnicki, M.A. (2012). Snail regulates MyoD binding-site occupancy to direct enhancer switching and differentiation-specific transcription in myogenesis. Molecular Cell 47:457-468. 

von Maltzahn, J., Bentzinger, C.F., and Rudnicki, M.A. (2012). Wnt7a-Fzd7 signalling directly activates the Akt/mTOR anabolic growth pathway in skeletal muscle. Nature Cell Biology 14:186-191.

Kawabe, Y., Wang, Y.X., McKinnell, I.W., Bedford, M.T., and Rudnicki, M.A. (2012). Carm1 regulates Pax7 transcriptional activity through MLL1/2 recruitment during asymmetric satellite stem cell divisions. Cell Stem Cell 11:333-345. 

Bentzinger, C.F., Wang, Y.X., von Maltzahn, J., Soleimani, V.D., Yin, H., and Rudnicki, M.A. (2013). Fibronectin regulates Wnt7a signaling and satellite cell expansion. Cell Stem Cell 12:75-87. 

For more publications, use this Pubmed ID link.

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Wang YX, Feige P, Brun CE, Hekmatnejad B, Dumont NA, Renaud JM, Faulkes S, Guindon DE, Rudnicki MA. EGFR-Aurka Signaling Rescues Polarity and Regeneration Defects in Dystrophin-Deficient Muscle Stem Cells by Increasing Asymmetric Divisions. Cell Stem Cell (2019),

Lukjanenko L, Karaz S, Stuelsatz P, Gurriaran-Rodriguez U, Michaud J, Dammone G, Sizzano F, Mashinchian O, Ancel S, Migliavacca E, Liot S, Jacot G, Metairon S, Raymond F, Descombes P, Palini A, Chazaud B, Rudnicki MA, Bentzinger CF, Feige JN. Aging Disrupts Muscle Stem Cell Function by Impairing Matricellular WISP1 Secretion from Fibro-Adipogenic Progenitors. Cell Stem Cell. 2019 Mar 7;24(3):433-446.e7. doi: 10.1016/j.stem.2018.12.014. Epub 2019 Jan 24.


Feige P, Brun CE, Ritso M, Rudnicki MA. Orienting Muscle Stem Cells for Regeneration in Homeostasis, Aging, and Disease. Cell Stem Cell. 2018 Nov 1;23(5):653-664. doi: 10.1016/j.stem.2018.10.006. Review. PubMed PMID: 30388423; PubMed Central PMCID: PMC6262894.

Soleimani VD, Nguyen D, Ramachandran P, Palidwor GA, Porter CJ, Yin H, Perkins TJ, Rudnicki MA. Cis-regulatory determinants of MyoD function. Nucleic Acids Res. 2018 Aug 21;46(14):7221-7235. doi: 10.1093/nar/gky388. PubMed PMID: 30016497; PubMed Central PMCID: PMC6101602.

Feige P, Rudnicki MA. Muscle stem cells. Curr Biol. 2018 May 21;28(10):R589-R590. doi: 10.1016/j.cub.2018.02.064. PubMed PMID: 29787715.

Bar-Nur O, Gerli MFM, Di Stefano B, Almada AE, Galvin A, Coffey A, Huebner AJ, Feige P, Verheul C, Cheung P, Payzin-Dogru D, Paisant S, Anselmo A, Sadreyev RI, Ott HC, Tajbakhsh S, Rudnicki MA, Wagers AJ, Hochedlinger K. Direct Reprogramming of Mouse Fibroblasts into Functional Skeletal Muscle Progenitors. Stem Cell Reports. 2018 May 8;10(5):1505-1521. doi: 10.1016/j.stemcr.2018.04.009. PubMed PMID: 29742392; PubMed Central PMCID: PMC5995754.

Chang NC, Sincennes MC, Chevalier FP, Brun CE, Lacaria M, Segalés J, Muñoz-Cánoves P, Ming H, Rudnicki MA. The Dystrophin Glycoprotein Complex Regulates the Epigenetic Activation of Muscle Stem Cell Commitment. Cell Stem Cell. 2018 May 3;22(5):755-768.e6. doi: 10.1016/j.stem.2018.03.022. Epub 2018 Apr 19.

Brun CE, Wang YX, Rudnicki MA. Single EDL Myofiber Isolation for Analyses of Quiescent and Activated Muscle Stem Cells. Methods Mol Biol. 2018;1686:149-159. doi: 10.1007/978-1-4939-7371-2_11.


Hernández-Hernández JM, García-González EG, Brun CE, Rudnicki MA. The myogenic regulatory factors, determinants of muscle development, cell identity and regeneration. Semin Cell Dev Biol. 2017 Dec;72:10-18. doi: 10.1016/j.semcdb.2017.11.010

Fraineau S, Palii CG, McNeill B, Ritso M, Shelley WC, Prasain N, Chu A, Vion E, Rieck K, Nilufar S, Perkins TJ, Rudnicki MA, Allan DS, Yoder MC, Suuronen EJ, Brand M. Epigenetic Activation of Pro-angiogenic Signaling Pathways in Human Endothelial Progenitors Increases Vasculogenesis. Stem Cell Reports 2017 Nov 14;9(5):1573-1587. doi: 10.1016/j.stemcr.2017.09.009.

Lacour F, Vezin E, Bentzinger CF, Sincennes MC, Giordani L, Ferry A, Mitchell R, Patel K, Rudnicki MA, Chaboissier MC, Chassot AA, Le Grand F. R-spondin1 Controls Muscle Cell Fusion through Dual Regulation of Antagonistic Wnt Signaling Pathways. Cell Rep. 2017 Mar 7;18(10):2320-2330. doi: 10.1016/j.celrep.2017.02.036. PubMed PMID: 28273449.

Sincennes MC, Wang YX, Rudnicki MA. Primary Mouse Myoblast Purification using Magnetic Cell Separation. Methods Mol Biol. 2017;1556:41-50. doi: 10.1007/978-1-4939-6771-1_3. PubMed PMID: 28247344.

Dumont NA, Rudnicki MA. Characterizing Satellite Cells and Myogenic Progenitors During Skeletal Muscle Regeneration. Methods Mol Biol. 2017;1560:179-188. doi: 10.1007/978-1-4939-6788-9_12. PubMed PMID: 28155153.


Al-Khalaf MH, Blake LE, Larsen BD, Bell RA, Brunette S, Parks RJ, Rudnicki MA, McKinnon PJ, Jeffrey Dilworth F, Megeney LA. Temporal activation of XRCC1-mediated DNA repair is essential for muscle differentiation. Cell Discov. 2016 Jan 12;2:15041. doi: 10.1038/celldisc.2015.41. eCollection 2016 Jan 12. PubMed PMID: 27462438

Lukjanenko L, Jung MJ, Hegde N, Perruisseau-Carrier C, Migliavacca E, Rozo M, Karaz S, Jacot G, Schmidt M, Li L, Metairon S, Raymond F, Lee U, Sizzano F, Wilson DH, Dumont NA, Palini A, Fässler R, Steiner P, Descombes P, Rudnicki MA, Fan CM, von Maltzahn J, Feige JN, Bentzinger CF. Loss of fibronectin from the aged stem cell niche affects the regenerative capacity of skeletal muscle in mice. Nat Med. 2016 Aug;22(8):897-905. doi: 10.1038/nm.4126. Epub 2016 Jul 4. PubMed PMID: 27376579.

Pasut A, Chang NC, Rodriguez UG, Faulkes S, Yin H, Lacaria M, Ming H, Rudnicki MA. Notch Signaling Rescues Loss of Satellite Cells Lacking Pax7 and Promotes Brown Adipogenic Differentiation. Cell Rep. 2016 Jul 12;16(2):333 43. doi: 10.1016/j.celrep.2016.06.001. Epub 2016 Jun 23. PubMed PMID: 27346341

Chang NC, Chevalier FP, Rudnicki MA. Satellite Cells in Muscular Dystrophy - Lost in Polarity. Trends Mol Med. 2016 Jun;22(6):479-96. doi: 10.1016/j.molmed.2016.04.002. Epub 2016 May 5. Review. PubMed PMID: 27161598

Jahani-Asl A, Yin H, Soleimani VD, Haque T, Luchman HA, Chang NC, Sincennes MC, Puram SV, Scott AM, Lorimer IA, Perkins TJ, Ligon KL, Weiss S, Rudnicki MA, Bonni A. Control of glioblastoma tumorigenesis by feed-forward cytokine signaling. Nat Neurosci. 2016 Jun;19(6):798-806. doi: 10.1038/nn.4295. Epub 2016 Apr 25. PubMed PMID: 27110918

Harper SC, Brack A, MacDonnell S, Franti M, Olwin BB, Bailey BA, Rudnicki MA, Houser SR. Is Growth Differentiation Factor 11 a Realistic Therapeutic for Aging-Dependent Muscle Defects? Circ Res. 2016 Apr 1;118(7):1143-50; discussion 1150. doi: 10.1161/CIRCRESAHA.116.307962. PubMed PMID: 27034276

McIntyre LA, Moher D, Fergusson DA, Sullivan KJ, Mei SH, Lalu M, Marshall J, Mcleod M, Griffin G, Grimshaw J, Turgeon A, Avey MT, Rudnicki MA, Jazi M, Fishman J, Stewart DJ; Canadian Critical Care Translational Biology Group.. Efficacy of Mesenchymal Stromal Cell Therapy for Acute Lung Injury in Preclinical Animal Models: A Systematic Review. PLoS One. 2016 Jan 28;11(1):e0147170. doi: 10.1371/journal.pone.0147170. eCollection 2016 Jan 28. Review. PubMed PMID: 26821255

Sincennes MC, Brun CE, Rudnicki MA. Concise Review: Epigenetic Regulation of Myogenesis in Health and Disease. Stem Cells Transl Med. 2016 Mar;5(3):282-90. doi: 10.5966/sctm.2015-0266. Epub 2016 Jan 21. Review. PubMed PMID: 26798058


Chihara D, Romer AI, Bentzinger CF, Rudnicki MA, Krauss RS. PAX7 is required for patterning the esophageal musculature. Skelet Muscle. 2015 Dec 3;5:39. doi: 10.1186/s13395-015-0068-0. eCollection 2015 Dec 3. PubMed PMID: 26635949; PubMed Central PMCID: PMC4668666.

Dumont NA, Wang YX, von Maltzahn J, Pasut A, Bentzinger CF, Brun CE, Rudnicki MA. Dystrophin expression in muscle stem cells regulates their polarity and asymmetric division. Nat Med. 2015 Dec;21(12):1455-63. doi: 10.1038/nm.3990. Epub 2015 Nov 16. PubMed PMID: 26569381; PubMed Central PMCID: PMC4839960.

Rudnicki MA, Williams BO. Wnt signaling in bone and muscle. Bone. 2015 Nov;80:60-6. doi: 10.1016/j.bone.2015.02.009. Review. PubMed PMID: 26453496; PubMed Central PMCID: PMC4600531.

Dick SA, Chang NC, Dumont NA, Bell RA, Putinski C, Kawabe Y, Litchfield DW, Rudnicki MA, Megeney LA. Caspase 3 cleavage of Pax7 inhibits self-renewal of satellite cells. Proc Natl Acad Sci U S A. 2015 Sep 22;112(38):E5246-52. doi: 10.1073/pnas.1512869112. Epub 2015 Sep 8. PubMed PMID: 26372956; PubMed Central PMCID: PMC4586827.

Dumont NA, Bentzinger CF, Sincennes MC, Rudnicki MA. Satellite Cells and Skeletal Muscle Regeneration. Compr Physiol. 2015 Jul 1;5(3):1027-59. doi: 10.1002/cphy.c140068. Review. PubMed PMID: 26140708.

Brun CE, Rudnicki MA. GDF11 and the Mythical Fountain of Youth. Cell Metab. 2015 Jul 7;22(1):54-6. doi: 10.1016/j.cmet.2015.05.009. Epub 2015 May 20. PubMed PMID: 26003784.

Jones AE, Price FD, Le Grand F, Soleimani VD, Dick SA, Megeney LA, Rudnicki MA. Wnt/ß-catenin controls follistatin signalling to regulate satellite cell myogenic potential. Skelet Muscle. 2015 Apr 28;5:14. doi: 10.1186/s13395-015-0038-6. eCollection 2015 Apr 28. PubMed PMID: 25949788; PubMed Central PMCID: PMC4421991.

Dumont NA, Wang YX, Rudnicki MA. Intrinsic and extrinsic mechanisms regulating satellite cell function. Development. 2015 May 1;142(9):1572-81. doi: 10.1242/dev.114223. Review. PubMed PMID: 25922523; PubMed Central PMCID: PMC4419274.

Price FD, von Maltzahn J, Bentzinger CF, Dumont NA, Yin H, Chang NC, Wilson DH, Frenette J, Rudnicki MA. Corrigendum: Inhibition of JAK-STAT signaling stimulates adult satellite cell function. Nat Med. 2015 Apr;21(4):414. doi: 10.1038/nm0415-414a. PubMed PMID: 25849274.


Smid JK, Faulkes S, Rudnicki MA. Periostin induces pancreatic regeneration. Endocrinology. 2015 Mar;156(3):824-36. doi: 10.1210/en.2014-1637. Epub 2014 Dec 8. PubMed PMID: 25485969.

Wang YX, Dumont NA, Rudnicki MA. Muscle stem cells at a glance. J Cell Sci. 2014 Nov 1;127(Pt 21):4543-8. doi: 10.1242/jcs.151209. Epub 2014 Oct 9. PubMed PMID: 25300792; PubMed Central PMCID: PMC4215708.

Price FD, von Maltzahn J, Bentzinger CF, Dumont NA, Yin H, Chang NC, Wilson DH, Frenette J, Rudnicki MA. Inhibition of JAK-STAT signaling stimulates adult satellite cell function. Nat Med. 2014 Oct;20(10):1174-81. doi: 10.1038/nm.3655. Epub 2014 Sep 7. Erratum in: Nat Med. 2015 Apr;21(4):414. Nat Med. 2014 Oct;(10):1217. PubMed PMID: 25194569; PubMed Central PMCID: PMC4191983.

Jiang C, Wen Y, Kuroda K, Hannon K, Rudnicki MA, Kuang S. Notch signaling deficiency underlies age-dependent depletion of satellite cells in muscular dystrophy. Dis Model Mech. 2014 Aug;7(8):997-1004. doi: 10.1242/dmm.015917. Epub 2014 Jun 6. PubMed PMID: 24906372; PubMed Central PMCID: PMC4107328.

Bentzinger CF, von Maltzahn J, Dumont NA, Stark DA, Wang YX, Nhan K, Frenette J, Cornelison DD, Rudnicki MA. Wnt7a stimulates myogenic stem cell motility and engraftment resulting in improved muscle strength. J Cell Biol. 2014 Apr 14;205(1):97-111. doi: 10.1083/jcb.201310035. Epub 2014 Apr 7. PubMed PMID: 24711502; PubMed Central PMCID: PMC3987134.

Bentzinger CF, Rudnicki MA. Rejuvenating aged muscle stem cells. Nat Med. 2014 Mar;20(3):234-5. doi: 10.1038/nm.3499. PubMed PMID: 24603790.

Glass DJ, Campbell KP, Rudnicki MA. Skeletal muscle's 3rd year anniversary. Skelet Muscle. 2014 Jan 24;4(1):3. doi: 10.1186/2044-5040-4-3. PubMed PMID: 24456943; PubMed Central PMCID: PMC3911964.

Chang NC, Rudnicki MA. Satellite cells: the architects of skeletal muscle. Curr Top Dev Biol. 2014;107:161-81. doi: 10.1016/B978-0-12-416022-4.00006-8. Review. PubMed PMID: 24439806.


von Maltzahn J, Zinoviev R, Chang NC, Bentzinger CF, Rudnicki MA. A truncated Wnt7a retains full biological activity in skeletal muscle. Nat Commun. 2013;4:2869. doi: 10.1038/ncomms3869. PubMed PMID: 24287629; PubMed Central PMCID: PMC3868162.

Bentzinger CF, Wang YX, Dumont NA, Rudnicki MA. Cellular dynamics in the muscle satellite cell niche. EMBO Rep. 2013 Dec;14(12):1062-72. doi: 10.1038/embor.2013.182. Epub 2013 Nov 15. Review. PubMed PMID: 24232182; PubMed Central PMCID: PMC3849491.

He WA, Berardi E, Cardillo VM, Acharyya S, Aulino P, Thomas-Ahner J, Wang J, Bloomston M, Muscarella P, Nau P, Shah N, Butchbach ME, Ladner K, Adamo S, Rudnicki MA, Keller C, Coletti D, Montanaro F, Guttridge DC. NF-?B-mediated Pax7 dysregulation in the muscle microenvironment promotes cancer cachexia. J Clin Invest. 2013 Nov;123(11):4821-35. PubMed PMID: 24084740; PubMed Central PMCID: PMC3809785.

von Maltzahn J, Jones AE, Parks RJ, Rudnicki MA. Pax7 is critical for the normal function of satellite cells in adult skeletal muscle. Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16474-9. doi: 10.1073/pnas.1307680110. Epub 2013 Sep 24. PubMed PMID: 24065826; PubMed Central PMCID: PMC3799311.

Liu W, Bi P, Shan T, Yang X, Yin H, Wang YX, Liu N, Rudnicki MA, Kuang S. miR-133a regulates adipocyte browning in vivo. PLoS Genet. 2013;9(7):e1003626. doi: 10.1371/journal.pgen.1003626. Epub 2013 Jul 11. PubMed PMID: 23874225; PubMed Central PMCID: PMC3708806.

Parker MH, von Maltzahn J, Bakkar N, Al-Joubori B, Ishibashi J, Guttridge D, Rudnicki MA. Retraction: MyoD-dependent regulation of NF-?B activity couples cell-cycle withdrawal to myogenic differentiation. Skelet Muscle. 2013 Jul 18;3(1):15. doi: 10.1186/2044-5040-3-15. PubMed PMID: 23870549; PubMed Central PMCID: PMC3717048.

Soleimani VD, Palidwor GA, Ramachandran P, Perkins TJ, Rudnicki MA. Chromatin tandem affinity purification sequencing. Nat Protoc. 2013 Aug;8(8):1525-34. doi: 10.1038/nprot.2013.088. Epub 2013 Jul 11. PubMed PMID: 23845964; PubMed Central PMCID: PMC4058862.

Wang YX, Bentzinger CF, Rudnicki MA. Treating muscular dystrophy by stimulating intrinsic repair. Regen Med. 2013 May;8(3):237-40. doi: 10.2217/rme.13.27. PubMed PMID: 23627818.

Pasut A, Jones AE, Rudnicki MA. Isolation and culture of individual myofibers and their satellite cells from adult skeletal muscle. J Vis Exp. 2013 Mar 22;(73):e50074. doi: 10.3791/50074. PubMed PMID: 23542587; PubMed Central PMCID: PMC3639710.

Kuroda K, Kuang S, Taketo MM, Rudnicki MA. Canonical Wnt signaling induces BMP-4 to specify slow myofibrogenesis of fetal myoblasts. Skelet Muscle. 2013 Mar 5;3(1):5. doi: 10.1186/2044-5040-3-5. PubMed PMID: 23497616; PubMed Central PMCID: PMC3602004.

Campbell PA, Rudnicki MA. Oct4 interaction with Hmgb2 regulates Akt signaling and pluripotency. Stem Cells. 2013 Jun;31(6):1107-20. doi: 10.1002/stem.1365. PubMed PMID: 23495099.

Yin H, Pasut A, Soleimani VD, Bentzinger CF, Antoun G, Thorn S, Seale P, Fernando P, van Ijcken W, Grosveld F, Dekemp RA, Boushel R, Harper ME, Rudnicki MA. MicroRNA-133 controls brown adipose determination in skeletal muscle satellite cells by targeting Prdm16. Cell Metab. 2013 Feb 5;17(2):210-24. doi: 10.1016/j.cmet.2013.01.004. PubMed PMID: 23395168; PubMed Central PMCID: PMC3641657.

Price FD, Yin H, Jones A, van Ijcken W, Grosveld F, Rudnicki MA. Canonical Wnt signaling induces a primitive endoderm metastable state in mouse embryonic stem cells. Stem Cells. 2013 Apr;31(4):752-64. doi: 10.1002/stem.1321. PubMed PMID: 23307624.

Yin H, Price F, Rudnicki MA. Satellite cells and the muscle stem cell niche. Physiol Rev. 2013 Jan;93(1):23-67. doi: 10.1152/physrev.00043.2011. Review. PubMed PMID: 23303905; PubMed Central PMCID: PMC4073943.

Bentzinger CF, Wang YX, von Maltzahn J, Soleimani VD, Yin H, Rudnicki MA. Fibronectin regulates Wnt7a signaling and satellite cell expansion. Cell Stem Cell. 2013 Jan 3;12(1):75-87. doi: 10.1016/j.stem.2012.09.015. PubMed PMID: 23290138; PubMed Central PMCID: PMC3539137.


Wang YX, Bentzinger CF, Rudnicki MA. Molecular regulation of determination in asymmetrically dividing muscle stem cells. Cell Cycle. 2013 Jan 1;12(1):3-4. doi: 10.4161/cc.23068. Epub 2012 Dec 19. PubMed PMID: 23255099; PubMed Central PMCID: PMC3570513.

von Maltzahn J, Renaud JM, Parise G, Rudnicki MA. Wnt7a treatment ameliorates muscular dystrophy. Proc Natl Acad Sci U S A. 2012 Dec 11;109(50):20614-9. doi: 10.1073/pnas.1215765109. Epub 2012 Nov 26. PubMed PMID: 23185011; PubMed Central PMCID: PMC3528612.

Huh MS, Price O'Dea T, Ouazia D, McKay BC, Parise G, Parks RJ, Rudnicki MA, Picketts DJ. Compromised genomic integrity impedes muscle growth after Atrx inactivation. J Clin Invest. 2012 Dec;122(12):4412-23. doi: 10.1172/JCI63765. Epub 2012 Nov 1. PubMed PMID: 23114596; PubMed Central PMCID: PMC3533543.

von Maltzahn J, Chang NC, Bentzinger CF, Rudnicki MA. Wnt signaling in myogenesis. Trends Cell Biol. 2012 Nov;22(11):602-9. doi: 10.1016/j.tcb.2012.07.008. Epub 2012 Aug 31. Review. PubMed PMID: 22944199; PubMed Central PMCID: PMC3479319.

Bentzinger CF, Wang YX, von Maltzahn J, Rudnicki MA. The emerging biology of muscle stem cells: implications for cell-based therapies. Bioessays. 2013 Mar;35(3):231-41. doi: 10.1002/bies.201200063. Epub 2012 Aug 6. Review. PubMed PMID: 22886714; PubMed Central PMCID: PMC3594813.

Kawabe Y, Wang YX, McKinnell IW, Bedford MT, Rudnicki MA. Carm1 regulates Pax7 transcriptional activity through MLL1/2 recruitment during asymmetric satellite stem cell divisions. Cell Stem Cell. 2012 Sep 7;11(3):333-45. doi: 10.1016/j.stem.2012.07.001. Epub 2012 Aug 2. PubMed PMID: 22863532; PubMed Central PMCID: PMC3438319.

Liu QC, Zha XH, Faralli H, Yin H, Louis-Jeune C, Perdiguero E, Pranckeviciene E, Muñoz-Cànoves P, Rudnicki MA, Brand M, Perez-Iratxeta C, Dilworth FJ. Comparative expression profiling identifies differential roles for Myogenin and p38a MAPK signaling in myogenesis. J Mol Cell Biol. 2012 Dec;4(6):386-97. doi: 10.1093/jmcb/mjs045. Epub 2012 Jul 30. PubMed PMID: 22847234; PubMed Central PMCID: PMC4580549.

Soleimani VD, Yin H, Jahani-Asl A, Ming H, Kockx CE, van Ijcken WF, Grosveld F, Rudnicki MA. Snail regulates MyoD binding-site occupancy to direct enhancer switching and differentiation-specific transcription in myogenesis. Mol Cell. 2012 Aug 10;47(3):457-68. doi: 10.1016/j.molcel.2012.05.046. Epub 2012 Jul 5. PubMed PMID: 22771117; PubMed Central PMCID: PMC4580277.

Rudnicki MA. Margaret Buckingham, discoveries in skeletal and cardiac muscle development, elected to the National Academy of Science. Skelet Muscle. 2012 Jun 7;2(1):12. doi: 10.1186/2044-5040-2-12. PubMed PMID: 22676886; PubMed Central PMCID: PMC3407767.

Soleimani VD, Punch VG, Kawabe Y, Jones AE, Palidwor GA, Porter CJ, Cross JW, Carvajal JJ, Kockx CE, van IJcken WF, Perkins TJ, Rigby PW, Grosveld F, Rudnicki MA. Transcriptional dominance of Pax7 in adult myogenesis is due to high-affinity recognition of homeodomain motifs. Dev Cell. 2012 Jun 12;22(6):1208-20. doi: 10.1016/j.devcel.2012.03.014. Epub 2012 May 17. PubMed PMID: 22609161; PubMed Central PMCID: PMC3376216.

Parker MH, von Maltzahn J, Bakkar N, Al-Joubori B, Ishibashi J, Guttridge D, Rudnicki MA. MyoD-dependent regulation of NF-?B activity couples cell-cycle withdrawal to myogenic differentiation. Skelet Muscle. 2012 May 19;2(1):6. doi: 10.1186/2044-5040-2-6. PubMed PMID: 22541644; PubMed Central PMCID: PMC3356597.

Yip DJ, Corcoran CP, Alvarez-Saavedra M, DeMaria A, Rennick S, Mears AJ, Rudnicki MA, Messier C, Picketts DJ. Snf2l regulates Foxg1-dependent progenitor cell expansion in the developing brain. Dev Cell. 2012 Apr 17;22(4):871-8. doi: 10.1016/j.devcel.2012.01.020. PubMed PMID: 22516202; PubMed Central PMCID: PMC4580287.

Pasut A, Rudnicki MA. The long, the short, and the micro: a polyA tale of Pax3 in satellite cells. Cell Stem Cell. 2012 Mar 2;10(3):237-8. doi: 10.1016/j.stem.2012.02.009. PubMed PMID: 22385651; PubMed Central PMCID: PMC3300070.

Bentzinger CF, Wang YX, Rudnicki MA. Building muscle: molecular regulation of myogenesis. Cold Spring Harb Perspect Biol. 2012 Feb 1;4(2). pii: a008342. doi: 10.1101/cshperspect.a008342. Review. PubMed PMID: 22300977; PubMed Central PMCID: PMC3281568.


Wang YX, Rudnicki MA. Satellite cells, the engines of muscle repair. Nat Rev Mol Cell Biol. 2011 Dec 21;13(2):127-33. doi: 10.1038/nrm3265. Review. PubMed PMID: 22186952.

von Maltzahn J, Bentzinger CF, Rudnicki MA. Wnt7a-Fzd7 signalling directly activates the Akt/mTOR anabolic growth pathway in skeletal muscle. Nat Cell Biol. 2011 Dec 18;14(2):186-91. doi: 10.1038/ncb2404. PubMed PMID: 22179044; PubMed Central PMCID: PMC3271181.

Pasut A, Oleynik P, Rudnicki MA. Isolation of muscle stem cells by fluorescence activated cell sorting cytometry. Methods Mol Biol. 2012;798:53 64. doi: 10.1007/978-1-61779-343-1_3. PubMed PMID: 22130830.

Glass DJ, Campbell KP, Rudnicki MA. Welcome to skeletal muscle. Skelet Muscle. 2011 Jan 24;1(1):1. doi: 10.1186/2044-5040-1-1. PubMed PMID: 21798079; PubMed Central PMCID: PMC3143905.

Krzyzanowski PM, Price FD, Muro EM, Rudnicki MA, Andrade-Navarro MA. Integration of expressed sequence tag data flanking predicted RNA secondary structures facilitates novel non-coding RNA discovery. PLoS One. 2011;6(6):e20561. doi: 10.1371/journal.pone.0020561. Epub 2011 Jun 15. PubMed PMID: 21698286; PubMed Central PMCID: PMC3115948.

Juan AH, Derfoul A, Feng X, Ryall JG, Dell'Orso S, Pasut A, Zare H, Simone JM, Rudnicki MA, Sartorelli V. Polycomb EZH2 controls self-renewal and safeguards the transcriptional identity of skeletal muscle stem cells. Genes Dev. 2011 Apr 15;25(8):789-94. doi: 10.1101/gad.2027911. PubMed PMID: 21498568; PubMed Central PMCID: PMC3078704.

Darabi R, Santos FN, Filareto A, Pan W, Koene R, Rudnicki MA, Kyba M, Perlingeiro RC. Assessment of the myogenic stem cell compartment following transplantation of Pax3/Pax7-induced embryonic stem cell-derived progenitors. Stem Cells. 2011 May;29(5):777-90. doi: 10.1002/stem.625. PubMed PMID: 21374762; PubMed Central PMCID: PMC3325545.

Soleimani VD, Rudnicki MA. New insights into the origin and the genetic basis of rhabdomyosarcomas. Cancer Cell. 2011 Feb 15;19(2):157-9. doi: 10.1016/j.ccr.2011.01.044. PubMed PMID: 21316595; PubMed Central PMCID: PMC4584399.

Zacharias AL, Lewandoski M, Rudnicki MA, Gage PJ. Pitx2 is an upstream activator of extraocular myogenesis and survival. Dev Biol. 2011 Jan 15;349(2):395-405. doi: 10.1016/j.ydbio.2010.10.028. Epub 2010 Oct 28. PubMed PMID: 21035439; PubMed Central PMCID: PMC3019256.


Jinno H, Morozova O, Jones KL, Biernaskie JA, Paris M, Hosokawa R, Rudnicki MA, Chai Y, Rossi F, Marra MA, Miller FD. Convergent genesis of an adult neural crest-like dermal stem cell from distinct developmental origins. Stem Cells. 2010 Nov;28(11):2027-40. doi: 10.1002/stem.525. PubMed PMID: 20848654; PubMed Central PMCID: PMC3087810.

Bentzinger CF, von Maltzahn J, Rudnicki MA. Extrinsic regulation of satellite cell specification. Stem Cell Res Ther. 2010 Aug 26;1(3):27. doi: 10.1186/scrt27. Review. PubMed PMID: 20804582; PubMed Central PMCID: PMC2941119.

Scimè A, Soleimani VD, Bentzinger CF, Gillespie MA, Le Grand F, Grenier G, Bevilacqua L, Harper ME, Rudnicki MA. Oxidative status of muscle is determined by p107 regulation of PGC-1alpha. J Cell Biol. 2010 Aug 23;190(4):651-62. doi: 10.1083/jcb.201005076. Epub 2010 Aug 16. PubMed PMID: 20713602; PubMed Central PMCID: PMC2928004.

Joe AW, Yi L, Natarajan A, Le Grand F, So L, Wang J, Rudnicki MA, Rossi FM. Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis. Nat Cell Biol. 2010 Feb;12(2):153-63. doi: 10.1038/ncb2015. Epub 2010 Jan 17. PubMed PMID: 20081841; PubMed Central PMCID: PMC4580288.


Gillespie MA, Le Grand F, Scimè A, Kuang S, von Maltzahn J, Seale V, Cuenda A, Ranish JA, Rudnicki MA. p38-{gamma}-dependent gene silencing restricts entry into the myogenic differentiation program. J Cell Biol. 2009 Dec 28;187(7):991-1005. doi: 10.1083/jcb.200907037. Epub 2009 Dec 21. PubMed PMID: 20026657; PubMed Central PMCID: PMC2806273.

Abou-Khalil R, Le Grand F, Pallafacchina G, Valable S, Authier FJ, Rudnicki MA, Gherardi RK, Germain S, Chretien F, Sotiropoulos A, Lafuste P, Montarras D, Chazaud B. Autocrine and paracrine angiopoietin 1/Tie-2 signaling promotes muscle satellite cell self-renewal. Cell Stem Cell. 2009 Sep 4;5(3):298-309. doi: 10.1016/j.stem.2009.06.001. PubMed PMID: 19733541; PubMed Central PMCID: PMC4592285.

Muro EM, McCann JA, Rudnicki MA, Andrade-Navarro MA. Use of SNP-arrays for ChIP assays: computational aspects. Methods Mol Biol. 2009;567:145-54. doi: 10.1007/978-1-60327-414-2_10. Review. PubMed PMID: 19588091.

Punch VG, Jones AE, Rudnicki MA. Transcriptional networks that regulate muscle stem cell function. Wiley Interdiscip Rev Syst Biol Med. 2009 Jul-Aug;1(1):128-40. doi: 10.1002/wsbm.11. Review. PubMed PMID: 20835986.

Le Grand F, Jones AE, Seale V, Scimè A, Rudnicki MA. Wnt7a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells. Cell Stem Cell. 2009 Jun 5;4(6):535-47. doi: 10.1016/j.stem.2009.03.013. PubMed PMID: 19497282; PubMed Central PMCID: PMC2743383.

Rudnicki MA, Le Grand F, McKinnell I, Kuang S. The molecular regulation of muscle stem cell function. Cold Spring Harb Symp Quant Biol. 2008;73:323-31. doi: 10.1101/sqb.2008.73.064. Epub 2009 Mar 27. Review. PubMed PMID: 19329572.


Seale P, Bjork B, Yang W, Kajimura S, Chin S, Kuang S, Scimè A, Devarakonda S, Conroe HM, Erdjument-Bromage H, Tempst P, Rudnicki MA, Beier DR, Spiegelman BM. PRDM16 controls a brown fat/skeletal muscle switch. Nature. 2008 Aug 21;454(7207):961-7. doi: 10.1038/nature07182. PubMed PMID: 18719582; PubMed Central PMCID: PMC2583329.

Lu A, Cummins JH, Pollett JB, Cao B, Sun B, Rudnicki MA, Huard J. Isolation of myogenic progenitor populations from Pax7-deficient skeletal muscle based on adhesion characteristics. Gene Ther. 2008 Aug;15(15):1116-25. doi: 10.1038/gt.2008.86. Epub 2008 May 29. PubMed PMID: 18509381.

Scimè A, Rudnicki MA. Molecular-targeted therapy for Duchenne muscular dystrophy: progress and potential. Mol Diagn Ther. 2008;12(2):99-108. Review. PubMed PMID: 18422374.

Kuang S, Gillespie MA, Rudnicki MA. Niche regulation of muscle satellite cell self-renewal and differentiation. Cell Stem Cell. 2008 Jan 10;2(1):22-31. doi: 10.1016/j.stem.2007.12.012. Review. PubMed PMID: 18371418.

Parise G, McKinnell IW, Rudnicki MA. Muscle satellite cell and atypical myogenic progenitor response following exercise. Muscle Nerve. 2008 May;37(5):611-9. doi: 10.1002/mus.20995. PubMed PMID: 18351585.

Bakkar N, Wang J, Ladner KJ, Wang H, Dahlman JM, Carathers M, Acharyya S, Rudnicki MA, Hollenbach AD, Guttridge DC. IKK/NF-kappaB regulates skeletal myogenesis via a signaling switch to inhibit differentiation and promote mitochondrial biogenesis. J Cell Biol. 2008 Feb 25;180(4):787-802. doi: 10.1083/jcb.200707179. PubMed PMID: 18299349; PubMed Central PMCID: PMC2265568.

Kuang S, Rudnicki MA. The emerging biology of satellite cells and their therapeutic potential. Trends Mol Med. 2008 Feb;14(2):82-91. doi: 10.1016/j.molmed.2007.12.004. Epub 2008 Jan 22. Review. PubMed PMID: 18218339.

McKinnell IW, Ishibashi J, Le Grand F, Punch VG, Addicks GC, Greenblatt JF, Dilworth FJ, Rudnicki MA. Pax7 activates myogenic genes by recruitment of a histone methyltransferase complex. Nat Cell Biol. 2008 Jan;10(1):77-84. Epub 2007 Dec 9. PubMed PMID: 18066051; PubMed Central PMCID: PMC2739814.


Holterman CE, Le Grand F, Kuang S, Seale P, Rudnicki MA. Megf10 regulates the progression of the satellite cell myogenic program. J Cell Biol. 2007 Dec 3;179(5):911-22. PubMed PMID: 18056409; PubMed Central PMCID: PMC2099186.

Le Grand F, Rudnicki MA. Skeletal muscle satellite cells and adult myogenesis. Curr Opin Cell Biol. 2007 Dec;19(6):628-33. Epub 2007 Nov 8. Review. PubMed PMID: 17996437; PubMed Central PMCID: PMC2215059.

Asakura A, Hirai H, Kablar B, Morita S, Ishibashi J, Piras BA, Christ AJ, Verma M, Vineretsky KA, Rudnicki MA. Increased survival of muscle stem cells lacking the MyoD gene after transplantation into regenerating skeletal muscle. Proc Natl Acad Sci U S A. 2007 Oct 16;104(42):16552-7. Epub 2007 Oct 10. PubMed PMID: 17940048; PubMed Central PMCID: PMC2034220.

McCann JA, Muro EM, Palmer C, Palidwor G, Porter CJ, Andrade-Navarro MA, Rudnicki MA. ChIP on SNP-chip for genome-wide analysis of human histone H4 hyperacetylation. BMC Genomics. 2007 Sep 14;8:322. PubMed PMID: 17868463; PubMed Central PMCID: PMC2194786.

Braun RK, Rudnicki MA, Sekaly RP, Filion LG. Filter selection for five color flow cytometric analysis with a single laser. Int J Lab Hematol. 2007 Oct;29(5):369-76. PubMed PMID: 17824918.

Grenier G, Scimè A, Le Grand F, Asakura A, Perez-Iratxeta C, Andrade-Navarro MA, Labosky PA, Rudnicki MA. Resident endothelial precursors in muscle, adipose, and dermis contribute to postnatal vasculogenesis. Stem Cells. 2007 Dec;25(12):3101-10. Epub 2007 Sep 6. PubMed PMID: 17823241.

Campbell PA, Perez-Iratxeta C, Andrade-Navarro MA, Rudnicki MA. Oct4 targets regulatory nodes to modulate stem cell function. PLoS One. 2007 Jun 20;2(6):e553. PubMed PMID: 17579724; PubMed Central PMCID: PMC1891092.

Kuang S, Kuroda K, Le Grand F, Rudnicki MA. Asymmetric self-renewal and commitment of satellite stem cells in muscle. Cell. 2007 Jun 1;129(5):999 1010. PubMed PMID: 17540178; PubMed Central PMCID: PMC2718740.

Hailesellasse Sene K, Porter CJ, Palidwor G, Perez-Iratxeta C, Muro EM, Campbell PA, Rudnicki MA, Andrade-Navarro MA. Gene function in early mouse embryonic stem cell differentiation. BMC Genomics. 2007 Mar 29;8:85. PubMed PMID: 17394647; PubMed Central PMCID: PMC1851713.


Parise G, O'Reilly CE, Rudnicki MA. Molecular regulation of myogenic progenitor populations. Appl Physiol Nutr Metab. 2006 Dec;31(6):773-81. PubMed PMID: 17213899.

Price FD, Kuroda K, Rudnicki MA. Stem cell based therapies to treat muscular dystrophy. Biochim Biophys Acta. 2007 Feb;1772(2):272-83. Epub 2006 Sep 6. Review. PubMed PMID: 17034994.

Parker MH, Perry RL, Fauteux MC, Berkes CA, Rudnicki MA. MyoD synergizes with the E-protein HEB beta to induce myogenic differentiation. Mol Cell Biol. 2006 Aug;26(15):5771-83. Erratum in: Mol Cell Biol. 2013 Nov;33(21):4357. PubMed PMID: 16847330; PubMed Central PMCID: PMC1592768.

Scimè A, Rudnicki MA. Anabolic potential and regulation of the skeletal muscle satellite cell populations. Curr Opin Clin Nutr Metab Care. 2006 May;9(3):214-9. Review. PubMed PMID: 16607119.

Kuang S, Chargé SB, Seale P, Huh M, Rudnicki MA. Distinct roles for Pax7 and Pax3 in adult regenerative myogenesis. J Cell Biol. 2006 Jan 2;172(1):103-13. PubMed PMID: 16391000; PubMed Central PMCID: PMC2063538.

Grenier G, Rudnicki MA. The potential use of myogenic stem cells in regenerative medicine. Handb Exp Pharmacol. 2006;(174):299-317. Review. PubMed PMID: 16370333.


McKinnell IW, Parise G, Rudnicki MA. Muscle stem cells and regenerative myogenesis. Curr Top Dev Biol. 2005;71:113-30. Review. PubMed PMID: 16344104.

Ishibashi J, Perry RL, Asakura A, Rudnicki MA. MyoD induces myogenic differentiation through cooperation of its NH2- and COOH-terminal regions. J Cell Biol. 2005 Nov 7;171(3):471-82. PubMed PMID: 16275751; PubMed Central PMCID: PMC2171269.

Scimè A, Grenier G, Huh MS, Gillespie MA, Bevilacqua L, Harper ME, Rudnicki MA. Rb and p107 regulate preadipocyte differentiation into white versus brown fat through repression of PGC-1alpha. Cell Metab. 2005 Nov;2(5):283-95. PubMed PMID: 16271529.

Huh MS, Smid JK, Rudnicki MA. Muscle function and dysfunction in health and disease. Birth Defects Res C Embryo Today. 2005 Sep;75(3):180-92. Review. PubMed PMID: 16187312.

Balciunaite E, Spektor A, Lents NH, Cam H, Te Riele H, Scime A, Rudnicki MA, Young R, Dynlacht BD. Pocket protein complexes are recruited to distinct targets in quiescent and proliferating cells. Mol Cell Biol. 2005 Sep;25(18):8166-78. PubMed PMID: 16135806; PubMed Central PMCID: PMC1234327.

Holterman CE, Rudnicki MA. Molecular regulation of satellite cell function. Semin Cell Dev Biol. 2005 Aug-Oct;16(4-5):575-84. Review. PubMed PMID: 16095933.

McKinnell IW, Rudnicki MA. Developmental biology: one source for muscle. Nature. 2005 Jun 16;435(7044):898-9. PubMed PMID: 15959503.

Perez-Iratxeta C, Palidwor G, Porter CJ, Sanche NA, Huska MR, Suomela BP, Muro EM, Krzyzanowski PM, Hughes E, Campbell PA, Rudnicki MA, Andrade MA. Study of stem cell function using microarray experiments. FEBS Lett. 2005 Mar 21;579(8):1795-801. Review. PubMed PMID: 15763554.


McKinnell IW, Rudnicki MA. Molecular mechanisms of muscle atrophy. Cell. 2004 Dec 29;119(7):907-10. PubMed PMID: 15620349.

Seale P, Ishibashi J, Holterman C, Rudnicki MA. Muscle satellite cell specific genes identified by genetic profiling of MyoD-deficient myogenic cell. Dev Biol. 2004 Nov 15;275(2):287-300. PubMed PMID: 15501219.

Huh MS, Parker MH, Scimè A, Parks R, Rudnicki MA. Rb is required for progression through myogenic differentiation but not maintenance of terminal differentiation. J Cell Biol. 2004 Sep 13;166(6):865-76. PubMed PMID: 15364961; PubMed Central PMCID: PMC2172111.

Gillespie MA, Rudnicki MA. Something to SNF about. Nat Genet. 2004 Jul;36(7):676-7. PubMed PMID: 15226749.

Seale P, Ishibashi J, Scimè A, Rudnicki MA. Pax7 is necessary and sufficient for the myogenic specification of CD45+:Sca1+ stem cells from injured muscle. PLoS Biol. 2004 May;2(5):E130. Epub 2004 May 11. PubMed PMID: 15138500; PubMed Central PMCID: PMC406392.

Komaki M, Asakura A, Rudnicki MA, Sodek J, Cheifetz S. MyoD enhances BMP7-induced osteogenic differentiation of myogenic cell cultures. J Cell Sci. 2004 Mar 15;117(Pt 8):1457-68. PubMed PMID: 15020674.

Chargé SB, Rudnicki MA. Cellular and molecular regulation of muscle regeneration. Physiol Rev. 2004 Jan;84(1):209-38. Review. PubMed PMID: 14715915.


Asakura A, Rudnicki MA. Rhabdomyosarcomagenesis-Novel pathway found. Cancer Cell. 2003 Dec;4(6):421-2. Review. PubMed PMID: 14706332.

Rudnicki MA. Marrow to muscle, fission versus fusion. Nat Med. 2003 Dec;9(12):1461-2. PubMed PMID: 14647520.

Inanlou MR, Dhillon GS, Belliveau AC, Reid GA, Ying C, Rudnicki MA, Kablar B. A significant reduction of the diaphragm in mdx:MyoD-/-(9th) embryos suggests a role for MyoD in the diaphragm development. Dev Biol. 2003 Sep 15;261(2):324-36. PubMed PMID: 14499644.

Seale P, Polesskaya A, Rudnicki MA. Adult stem cell specification by Wnt signaling in muscle regeneration. Cell Cycle. 2003 Sep-Oct;2(5):418-9. Review. PubMed PMID: 12963830.

Parker MH, Seale P, Rudnicki MA. Looking back to the embryo: defining transcriptional networks in adult myogenesis. Nat Rev Genet. 2003 Jul;4(7):497-507. Review. PubMed PMID: 12838342.

Polesskaya A, Seale P, Rudnicki MA. Wnt signaling induces the myogenic specification of resident CD45+ adult stem cells during muscle regeneration. Cell. 2003 Jun 27;113(7):841-52. PubMed PMID: 12837243.

Wang ZZ, Washabaugh CH, Yao Y, Wang JM, Zhang L, Ontell MP, Watkins SC, Rudnicki MA, Ontell M. Aberrant development of motor axons and neuromuscular synapses in MyoD-null mice. J Neurosci. 2003 Jun 15;23(12):5161-9. PubMed PMID: 12832540.

Kablar B, Krastel K, Tajbakhsh S, Rudnicki MA. Myf5 and MyoD activation define independent myogenic compartments during embryonic development. Dev Biol. 2003 Jun 15;258(2):307-18. PubMed PMID: 12798290.

Chargé S, Rudnicki MA. Fusion with the fused: a new role for interleukin-4 in the building of muscle. Cell. 2003 May 16;113(4):422-3. Review. PubMed PMID: 12757701.


Kablar B, Rudnicki MA. Information provided by the skeletal muscle and associated neurons is necessary for proper brain development. Int J Dev Neurosci. 2002 Nov;20(7):573-84. PubMed PMID: 12485625.

Polesskaya A, Rudnicki MA. A MyoD-dependent differentiation checkpoint: ensuring genome integrity. Dev Cell. 2002 Dec;3(6):757-8. Review. PubMed PMID: 12479798.

Asakura A, Rudnicki MA. Side population cells from diverse adult tissues are capable of in vitro hematopoietic differentiation. Exp Hematol. 2002 Nov;30(11):1339-45. PubMed PMID: 12423688.

Hierlihy AM, Seale P, Lobe CG, Rudnicki MA, Megeney LA. The post-natal heart contains a myocardial stem cell population. FEBS Lett. 2002 Oct 23;530(1-3):239-43. PubMed PMID: 12387899.

Asakura A, Seale P, Girgis-Gabardo A, Rudnicki MA. Myogenic specification of side population cells in skeletal muscle. J Cell Biol. 2002 Oct 14;159(1):123-34. Epub 2002 Oct 14. PubMed PMID: 12379804; PubMed Central PMCID: PMC2173497.

Mukhopadhyay M, Pelka P, DeSousa D, Kablar B, Schindler A, Rudnicki MA, Campos AR. Cloning, genomic organization and expression pattern of a novel Drosophila gene, the disco-interacting protein 2 (dip2), and its murine homolog. Gene. 2002 Jun 26;293(1-2):59-65. PubMed PMID: 12137943.

Andrechek ER, Hardy WR, Girgis-Gabardo AA, Perry RL, Butler R, Graham FL, Kahn RC, Rudnicki MA, Muller WJ. ErbB2 is required for muscle spindle and myoblast cell survival. Mol Cell Biol. 2002 Jul;22(13):4714-22. PubMed PMID: 12052879; PubMed Central PMCID: PMC133917.

Bergstrom DA, Penn BH, Strand A, Perry RL, Rudnicki MA, Tapscott SJ. Promoter-specific regulation of MyoD binding and signal transduction cooperate to pattern gene expression. Mol Cell. 2002 Mar;9(3):587-600. PubMed PMID: 11931766.


Seale P, Asakura A, Rudnicki MA. The potential of muscle stem cells. Dev Cell. 2001 Sep;1(3):333-42. Review. PubMed PMID: 11702945.

Perry RL, Parker MH, Rudnicki MA. Activated MEK1 binds the nuclear MyoD transcriptional complex to repress transactivation. Mol Cell. 2001 Aug;8(2):291-301. PubMed PMID: 11545732.

Kolodziejczyk SM, Walsh GS, Balazsi K, Seale P, Sandoz J, Hierlihy AM, Rudnicki MA, Chamberlain JS, Miller FD, Megeney LA. Activation of JNK1 contributes to dystrophic muscle pathogenesis. Curr Biol. 2001 Aug 21;11(16):1278-82. PubMed PMID: 11525743.

Wang SP, Laurin N, Himms-Hagen J, Rudnicki MA, Levy E, Robert MF, Pan L, Oligny L, Mitchell GA. The adipose tissue phenotype of hormone-sensitive lipase deficiency in mice. Obes Res. 2001 Feb;9(2):119-28. PubMed PMID: 11316346.

Seward DJ, Haney JC, Rudnicki MA, Swoap SJ. bHLH transcription factor MyoD affects myosin heavy chain expression pattern in a muscle-specific fashion. Am J Physiol Cell Physiol. 2001 Feb;280(2):C408-13. PubMed PMID: 11208536.

Chen Z, Karaplis AC, Ackerman SL, Pogribny IP, Melnyk S, Lussier-Cacan S, Chen MF, Pai A, John SW, Smith RS, Bottiglieri T, Bagley P, Selhub J, Rudnicki MA, James SJ, Rozen R. Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition. Hum Mol Genet. 2001 Mar 1;10(5):433-43. PubMed PMID: 11181567.


Laing MA, Coonrod S, Hinton BT, Downie JW, Tozer R, Rudnicki MA, Hassell JA. Male sexual dysfunction in mice bearing targeted mutant alleles of the PEA3 ets gene. Mol Cell Biol. 2000 Dec;20(24):9337-45. PubMed PMID: 11094084; PubMed Central PMCID: PMC102190.

White JD, Scaffidi A, Davies M, McGeachie J, Rudnicki MA, Grounds MD. Myotube formation is delayed but not prevented in MyoD-deficient skeletal muscle:studies in regenerating whole muscle grafts of adult mice. J Histochem Cytochem. 2000 Nov;48(11):1531-44. PubMed PMID: 11036096.

Seale P, Sabourin LA, Girgis-Gabardo A, Mansouri A, Gruss P, Rudnicki MA. Pax7 is required for the specification of myogenic satellite cells. Cell. 2000 Sep 15;102(6):777-86. PubMed PMID: 11030621.

Cornelison DD, Olwin BB, Rudnicki MA, Wold BJ. MyoD(-/-) satellite cells in single-fiber culture are differentiation defective and MRF4 deficient. Dev Biol. 2000 Aug 15;224(2):122-37. PubMed PMID: 10926754.

Kablar B, Rudnicki MA. Skeletal muscle development in the mouse embryo. Histol Histopathol. 2000 Apr;15(2):649-56. Review. PubMed PMID: 10809386.

Sabourin LA, Rudnicki MA. The molecular regulation of myogenesis. Clin Genet. 2000 Jan;57(1):16-25. Review. PubMed PMID: 10733231.

Kablar B, Tajbakhsh S, Rudnicki MA. Transdifferentiation of esophageal smooth to skeletal muscle is myogenic bHLH factor-dependent. Development. 2000 Apr;127(8):1627-39. PubMed PMID: 10725239.

Andrechek ER, Hardy WR, Siegel PM, Rudnicki MA, Cardiff RD, Muller WJ. Amplification of the neu/erbB-2 oncogene in a mouse model of mammary tumorigenesis. Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3444-9. PubMed PMID: 10716706; PubMed Central PMCID: PMC16259.

Seale P, Rudnicki MA. A new look at the origin, function, and "stem cell" status of muscle satellite cells. Dev Biol. 2000 Feb 15;218(2):115-24. Review. PubMed PMID: 10656756.

Sabourin LA, Tamai K, Seale P, Wagner J, Rudnicki MA. Caspase 3 cleavage of the Ste20-related kinase SLK releases and activates an apoptosis-inducing kinase domain and an actin-disassembling region. Mol Cell Biol. 2000 Jan;20(2):684-96. Erratum in: Mol Cell Biol 2000 Apr;20(8):2949. PubMed PMID: 10611247; PubMed Central PMCID: PMC85169.


Sabourin LA, Rudnicki MA. Induction of apoptosis by SLK, a Ste20-related kinase. Oncogene. 1999 Dec 9;18(52):7566-75. PubMed PMID: 10602516.

Kablar B, Asakura A, Krastel K, Ying C, May LL, Goldhamer DJ, Rudnicki MA. MyoD and Myf-5 define the specification of musculature of distinct embryonic origin. Biochem Cell Biol. 1998;76(6):1079-91. PubMed PMID: 10392718.

Yablonka-Reuveni Z, Rudnicki MA, Rivera AJ, Primig M, Anderson JE, Natanson P. The transition from proliferation to differentiation is delayed in satellite cells from mice lacking MyoD. Dev Biol. 1999 Jun 15;210(2):440-55. PubMed PMID:10357902

Kablar B, Rudnicki MA. Development in the absence of skeletal muscle results in the sequential ablation of motor neurons from the spinal cord to the brain. Dev Biol. 1999 Apr 1;208(1):93-109. PubMed PMID: 10075844.

Sabourin LA, Girgis-Gabardo A, Seale P, Asakura A, Rudnicki MA. Reduced differentiation potential of primary MyoD-/- myogenic cells derived from adult skeletal muscle. J Cell Biol. 1999 Feb 22;144(4):631-43. PubMed PMID: 10037786

Kablar B, Krastel K, Ying C, Tapscott SJ, Goldhamer DJ, Rudnicki MA. Myogenic determination occurs independently in somites and limb buds. Dev Biol. 1999 Feb 15;206(2):219-31. PubMed PMID: 9986734.

Megeney LA, Kablar B, Perry RL, Ying C, May L, Rudnicki MA. Severe cardiomyopathy in mice lacking dystrophin and MyoD. Proc Natl Acad Sci U S A. 1999 Jan 5;96(1):220-5. PubMed PMID: 9874799

LeCouter JE, Kablar B, Hardy WR, Ying C, Megeney LA, May LL, Rudnicki MA. Strain-dependent myeloid hyperplasia, growth deficiency, and accelerated cell cycle in mice lacking the Rb-related p107 gene. Mol Cell Biol. 1998 Dec;18(12):7455-65. PubMed PMID: 9819431

LeCouter JE, Kablar B, Whyte PF, Ying C, Rudnicki MA. Strain-dependent embryonic lethality in mice lacking the retinoblastoma-related p130 gene. Development. 1998 Dec;125(23):4669-79. PubMed PMID: 9806916.

McIntosh LM, Garrett KL, Megeney L, Rudnicki MA, Anderson JE. Regeneration and myogenic cell proliferation correlate with taurine levels in dystrophin- and MyoD-deficient muscles. Anat Rec. 1998 Oct;252(2):311-24. PubMed PMID: 9776086.

Kablar B, Krastel K, Ying C, Asakura A, Tapscott SJ, Rudnicki MA. MyoD and Myf-5 differentially regulate the development of limb versus trunk skeletal muscle. Development. 1997 Dec;124(23):4729-38. PubMed PMID: 9428409.

Parks RJ, Chen L, Anton M, Sankar U, Rudnicki MA, Graham FL. A helper-dependent adenovirus vector system: removal of helper virus by Cre-mediated excision of the viral packaging signal. Proc Natl Acad Sci U S A. 1996 Nov 26;93(24):13565-70. PubMed PMID: 8942974

Tiidus PM, Bombardier E, Xeni J, Bestic NM, Vandenboom R, Rudnicki MA, Houston ME. Elevated catalase activity in red and white muscles of MyoD gene-inactivated mice. Biochem Mol Biol Int. 1996 Aug;39(5):1029-35. PubMed PMID:8866021.

Megeney LA, Kablar B, Garrett K, Anderson JE, Rudnicki MA. MyoD is required for myogenic stem cell function in adult skeletal muscle. Genes Dev. 1996 May 15;10(10):1173-83. PubMed PMID: 8675005.

LeCouter JE, Whyte PF, Rudnicki MA. Cloning and expression of the Rb-related mouse p130 mRNA. Oncogene. 1996 Apr 4;12(7):1433-40. PubMed PMID: 8622859.

Megeney LA, Perry RL, LeCouter JE, Rudnicki MA. bFGF and LIF signaling activates STAT3 in proliferating myoblasts. Dev Genet. 1996;19(2):139-45. PubMed PMID: 8900046.

Megeney LA, Rudnicki MA. Determination versus differentiation and the MyoD family of transcription factors. Biochem Cell Biol. 1995 Sep-Oct;73(9-10):723-32. Review. PubMed PMID: 8714693.

Metzger JM, Rudnicki MA, Westfall MV. Altered Ca2+ sensitivity of tension in single skeletal muscle fibres from MyoD gene-inactivated mice. J Physiol. 1995 Jun 1;485 (Pt 2):447-53. PubMed PMID: 7666367

Rudnicki MA, Jaenisch R. The MyoD family of transcription factors and skeletal myogenesis. Bioessays. 1995 Mar;17(3):203-9. Review. PubMed PMID: 7748174.

Braun T, Bober E, Rudnicki MA, Jaenisch R, Arnold HH. MyoD expression marks the onset of skeletal myogenesis in Myf-5 mutant mice. Development. 1994 Nov;120(11):3083-92. PubMed PMID: 7720554.

Rudnicki MA, Schnegelsberg PN, Stead RH, Braun T, Arnold HH, Jaenisch R. MyoD or Myf-5 is required for the formation of skeletal muscle. Cell. 1993 Dec 31;75(7):1351-9. PubMed PMID: 8269513.

Mombaerts P, Clarke AR, Rudnicki MA, Iacomini J, Itohara S, Lafaille JJ, Wang L, Ichikawa Y, Jaenisch R, Hooper ML, et al. Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages. Nature. 1992 Nov 19;360(6401):225-31. Erratum in: Nature 1992 Dec 3;360(6403):491. PubMed PMID: 1359428.

Braun T, Rudnicki MA, Arnold HH, Jaenisch R. Targeted inactivation of the muscle regulatory gene Myf-5 results in abnormal rib development and perinatal death. Cell. 1992 Oct 30;71(3):369-82. PubMed PMID: 1423602.

Rudnicki MA, Braun T, Hinuma S, Jaenisch R. Inactivation of MyoD in mice leads to up-regulation of the myogenic HLH gene Myf-5 and results in apparently normal muscle development. Cell. 1992 Oct 30;71(3):383-90. PubMed PMID: 1330322.

McBurney MW, Sutherland LC, Adra CN, Leclair B, Rudnicki MA, Jardine K. The mouse Pgk-1 gene promoter contains an upstream activator sequence. Nucleic Acids Res. 1991 Oct 25;19(20):5755-61. PubMed PMID: 1945853

Laird PW, Zijderveld A, Linders K, Rudnicki MA, Jaenisch R, Berns A. Simplified mammalian DNA isolation procedure. Nucleic Acids Res. 1991 Aug 11;19(15):4293. PubMed PMID: 1870982

Rudnicki MA, Jackowski G, Saggin L, McBurney MW. Actin and myosin expression during development of cardiac muscle from cultured embryonal carcinoma cells. Dev Biol. 1990 Apr;138(2):348-58. PubMed PMID: 2318340.

Rudnicki MA, Sawtell NM, Reuhl KR, Berg R, Craig JC, Jardine K, Lessard JL, McBurney MW. Smooth muscle actin expression during P19 embryonal carcinoma differentiation in cell culture. J Cell Physiol. 1990 Jan;142(1):89-98. PubMed PMID: 2404996.

Rudnicki MA, Reuhl KR, McBurney MW. Cell lines with developmental potential restricted to mesodermal lineages isolated from differentiating cultures of pluripotential P19 embryonal carcinoma cells. Development. 1989 Oct;107(2):361-72. PubMed PMID: 2483683.

Rudnicki MA, Reuhl KR, McBurney MW. A transfected H-ras oncogene does not inhibit differentiation of cardiac and skeletal muscle from embryonal carcinoma cells. Biochem Cell Biol. 1989 Sep;67(9):590-6. PubMed PMID: 2679803.

Ruben MM, Rudnicki MA, Bladon TS, Jardine K, Craig J, McBurney MW. Expression of the human cardiac actin gene in differentiating rat skeletal myoblasts. Biochim Biophys Acta. 1988 Sep 7;950(3):374-84. PubMed PMID: 2844260.

Rudnicki MA, Ruben M, McBurney MW. Regulated expression of a transfected human cardiac actin gene during differentiation of multipotential murine embryonal carcinoma cells. Mol Cell Biol. 1988 Jan;8(1):406-17. PubMed PMID:3275877

Jones-Villeneuve EM, Rudnicki MA, Harris JF, McBurney MW. Retinoic acid-induced neural differentiation of embryonal carcinoma cells. Mol Cell Biol. 1983 Dec;3(12):2271-9. PubMed PMID: 6656766